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Mladen Korbelik Selected Research

Photochemotherapy (Photodynamic Therapy)

1/2022Controlling Immunoregulatory Cell Activity for Effective Photodynamic Therapy of Cancer.
8/2021Optimization of Whole Tumor Cell Vaccines by Interaction with Phagocytic Receptors.
4/2021Photodynamic Therapy as an Oxidative Anti-Tumor Modality: Negative Effects of Nitric Oxide on Treatment Efficacy.
9/2020Mechanistic insights into ceramidase inhibitor LCL521-enhanced tumor cell killing by photodynamic and thermal ablation therapies.
1/2020Preclinical and Clinical Evidence of Immune Responses Triggered in Oncologic Photodynamic Therapy: Clinical Recommendations.
10/2019N-dihydrogalactochitosan as immune and direct antitumor agent amplifying the effects of photodynamic therapy and photodynamic therapy-generated vaccines.
1/2018Role of cell stress signaling networks in cancer cell death and antitumor immune response following proteotoxic injury inflicted by photodynamic therapy.
10/2016Mreg Activity in Tumor Response to Photodynamic Therapy and Photodynamic Therapy-Generated Cancer Vaccines.
6/2016Enhanced apoptotic cancer cell killing after Foscan photodynamic therapy combined with fenretinide via de novo sphingolipid biosynthesis pathway.
1/2016Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine.
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Mladen Korbelik Research Topics

Disease

50Neoplasms (Cancer)
01/2022 - 09/2002
16Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2020 - 09/2002
5Squamous Cell Carcinoma of Head and Neck
01/2017 - 12/2013
5Acute-Phase Reaction
09/2012 - 03/2006
5Lewis Lung Carcinoma
10/2011 - 05/2007
4Fibrosarcoma
11/2009 - 03/2006
3Carcinoma (Carcinomatosis)
11/2009 - 07/2005
3Inflammation (Inflammations)
03/2008 - 10/2003
3Wounds and Injuries (Trauma)
05/2007 - 06/2006
1Head and Neck Neoplasms (Head and Neck Cancer)
01/2016
1Photosensitivity Disorders (Photodermatitis)
11/2014
1Cadaver (Cadavers)
06/2013

Drug/Important Bio-Agent (IBA)

501-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2022 - 04/2002
17Photosensitizing Agents (Photosensitizers)IBA
01/2020 - 04/2002
14Dihematoporphyrin Ether (Porfimer Sodium)FDA Link
09/2013 - 09/2002
11VaccinesIBA
08/2021 - 08/2006
11Complement System Proteins (Complement)IBA
06/2013 - 08/2004
7CeramidesIBA
09/2020 - 09/2011
7Acute-Phase Proteins (Acute-Phase Protein)IBA
06/2013 - 08/2006
6Therapeutic UsesIBA
11/2015 - 01/2006
5temoporfinIBA
09/2020 - 10/2003
5SphingolipidsIBA
01/2017 - 09/2013
5Proteins (Proteins, Gene)FDA Link
06/2013 - 08/2006
4Neoplasm Antigens (Tumor Antigens)IBA
01/2021 - 06/2006
4dihydroceramide desaturaseIBA
01/2017 - 09/2013
4silicon phthalocyanineIBA
05/2015 - 09/2013
4Serum Amyloid P-ComponentIBA
06/2013 - 12/2007
3LCL521IBA
01/2022 - 01/2016
3Acid CeramidaseIBA
01/2022 - 01/2016
3Pharmaceutical PreparationsIBA
01/2021 - 04/2002
3Cancer VaccinesIBA
10/2019 - 11/2015
3GlucocorticoidsIBA
09/2012 - 03/2008
3HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
09/2012 - 02/2005
3Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2011 - 02/2005
3Complement C3 (C3 Complement)IBA
09/2007 - 08/2006
2AntibodiesIBA
08/2021 - 05/2012
2N-dihydrogalactochitosanIBA
01/2021 - 03/2020
2sphingosine kinaseIBA
09/2020 - 09/2013
2fumonisin B1IBA
01/2017 - 11/2014
2Caspase 3 (Caspase-3)IBA
01/2017 - 12/2013
2FenretinideIBA
06/2016 - 05/2015
2CalreticulinIBA
01/2015 - 10/2011
2sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
06/2014 - 05/2012
2EnzymesIBA
09/2013 - 10/2003
2C-Reactive ProteinIBA
06/2013 - 03/2008
2SuspensionsIBA
05/2012 - 09/2011
2hypocrellin AIBA
01/2012 - 11/2009
2Oxygen (Dioxygen)IBA
07/2011 - 09/2007
2Hormones (Hormone)IBA
12/2010 - 03/2008
2ElementsIBA
05/2007 - 01/2006
2Coloring Agents (Dyes)IBA
01/2006 - 01/2005
1Scavenger Receptors (Scavenger Receptor)IBA
08/2021
1Nitric Oxide (Nitrogen Monoxide)FDA Link
04/2021
1Free RadicalsIBA
04/2021
1Phosphates (Orthophosphate)IBA
09/2020
1PF-543IBA
09/2020
1SphingosineIBA
09/2020
1CeramidasesIBA
09/2020
1Biopolymers (Biopolymer)IBA
03/2020
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2020
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2015
1Tretinoin (Retinoic Acid)FDA LinkGeneric
11/2015
1Opsonin Proteins (Opsonins)IBA
08/2015
1retinamideIBA
05/2015
1phthalocyanineIBA
12/2013
1SiliconesIBA
12/2013
1Dasatinib (BMS 354825)FDA Link
12/2013
1PorphyrinsIBA
09/2013
1D- erythro- 2- N- (160- (1''- pyridinium)hexadecanoyl)sphingosine bromideIBA
09/2013
1N-palmitoylsphingosineIBA
09/2013
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
06/2013
1serum-glucocorticoid regulated kinaseIBA
09/2012
1Povidone (Crospovidone)IBA
01/2012
1HMGB1 Protein (HMG1)IBA
10/2011
1N-caproylsphingosineIBA
09/2011
1CalciumIBA
09/2011
1CaspasesIBA
09/2011
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
03/2011
1CorticosteroneIBA
12/2010
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
12/2010
1Carbon Nanotubes (Carbon Nanotube)IBA
11/2010
1Interferon-gamma (Interferon, gamma)IBA
11/2009
1hypocrellin BIBA
11/2009
1Toll-Like Receptors (Toll-Like Receptor)IBA
08/2009
1ProperdinIBA
10/2008
1CD55 Antigens (Decay Accelerating Factor)IBA
10/2008
1Complement Factor H (Factor H)IBA
10/2008
1CD59 AntigensIBA
10/2008
1Interleukin-6 (Interleukin 6)IBA
03/2008
1Mannose-Binding Lectin (Mannan-Binding Lectin)IBA
03/2008

Therapy/Procedure

44Photochemotherapy (Photodynamic Therapy)
01/2022 - 09/2002
18Therapeutics
01/2022 - 08/2004
5Immunotherapy
10/2019 - 01/2005
4Photothermal Therapy
09/2020 - 01/2006
3Lasers (Laser)
11/2010 - 01/2005
1Drug Therapy (Chemotherapy)
04/2021
1Radiotherapy
04/2021
1Cryosurgery
09/2020
1Induced Hyperthermia (Thermotherapy)
11/2010
1Aftercare (After-Treatment)
11/2010